3 Days In Chicago, Ill.

It’s a city of firsts. The former Home Insurance Building, completed in 1884, was the world’s first ten-story “skyscraper.” In 1942, Enrico Fermi conducted the first controlled nuclear reaction on a squash court at the University of Chicago. And deep dish pizza made its first commercial appearance in 1943, when Ike Sewell and Ric Riccardo opened the restaurant now known as Pizzeria Uno.